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Committee

Ken Poole

As a practicing rheumatologist with a special interest in bone disorders my clinical work is based at Addenbrooke's Hospital, Cambridge working as part of a large group that includes Jonathan Reeve, Nigel Loveridge, Paul Mayhew, Juliet Compston, Adrian Crisp, Frances Hall and Hill Gaston.

I gained my PhD from Clare College, Cambridge in 2006 as an MRC Clinical Fellow, training in a broad range of clinical and laboratory bone research techniques while continuing my outpatient medical practice in rheumatology. Publications arising from this period included a successful RCT using intravenous bisphosphonates to prevent bone loss after stroke, the identification of vitamin D deficiency as a predictor of stroke, a histomorphometric analysis of iliac crest biopsies during stroke recovery and an in vivo study of osteocytes as inhibitors of bone formation (via sclerostin).

My review articles have focused on bone loss after stroke, the role of parathyroid hormone in bone anabolism and the management of osteoporosis. As a new principal investigator and ARC clinician scientist (since 2007), my ongoing translational research studies focus on the development of novel imaging biomarkers of hip fragility using clinical CT.



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