Wednesday 9 July

11:00

Registration and coffee

11:30

Official Opening

Bob Boucher, Vice-Chancellor, University of Sheffield

11:45

Oral Communications

Chairs: Tim Chambers (London, UK)/Greg Mundy (San Antonio TX, USA)

11:45

OC1 LIMITIN, A TYPE-I INTERFERON-LIKE CYTOKINE, INHIBITS OSTEOCLASTOGENESIS WITHOUT AFFECTING MACROPHAGE PROLIFERATION AND FUNCTION

T Sato, Y Hakeda. Department of Oral Anatomy, Meikai University, School of Dentistry, Saitama, Japan

11:57

OC2 MATRIX METALLOPROTEINASE INHIBITION DOES NOT RECAPITULATE THE ACTION OF CHEMICALLY MODIFIED TETRACYCLINES ON OSTEOCLAST LINEAGE CELLS

S G Holmes^[1], D J Buttle^[2], N J Bishop^[1], P S Grabowski^[1]. ^[1]Academic Unit of Child Health; ^[2]Division of Genomic Medicine, University of Sheffield, UK

12:09

OC3 ZOLEDRONIC ACID INHIBITS ADHESION OF BREAST AND PROSTATE CANCER CELLS VIA INHIBITION OF PROTEIN PRENYLATION

J P Coxon, L M Pickering, K W Colston. Department of Cellular & Molecular Medicine, St George's Hospital Medical School, London, UK

12:21

OC4 VISUALISATION OF THE UPTAKE OF A NOVEL FLUORESECENT BISPHOSPHONATE INTO INTRACELLULAR VESICLES IN RESORBING OSTEOCLASTS AND J774 CELLS

F P Coxon, J Langton, M J Rogers. Bone Research Group, University of Aberdeen, UK

12:33

OC5 DISTINCT REGULATION OF BONE AND MUSCLE MAINTENANCE DURING HINDLIMB SUSPENSION BY A CONCENTRIC RESISTANCE EXERCISE REGIMEN

D S Perrien^[1], N S Akel^[1], D C Montague^[1], M Knox^[2], J D Fluckey^[2], E E Dupont-Versteegden^[2], C A Peterson^[2], L Suva^[1], D Gaddy^[1]. ^[1]Physiology and Biophysics, and Center for Orthopaedic Research, Orthopaedic Surgery; ^[2]Geriatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

12:45

Lunch

13:45

Symposium: New thoughts about old hormones

Chairs: Cyrus Cooper (Southampton, UK)/Gordon Strewler (Boston MA, USA)

13:45

IS1 Vitamin D: Mike Holick (Boston MA, USA)

14:15

IS2 Parathyroid hormone: Ed Nemeth (Toronto, Canada)

14:45

Tea and Posters

16:00

Symposium: Hearts and bones

Chairs: Richard Eastell (Sheffield, UK)/Mike Rogers (Aberdeen, UK)

16:00

IS3 Statins and bone: Greg Mundy (San Antonio TX, USA)

16:30

IS4 Atherosclerosis: an inflammatory disease with calcification: David Crossman (Sheffield, UK)

17:00

IS5 The Barker Hypothesis: Early life influences on bone and cardiovascular diseases: Cyrus Cooper (Southampton, UK)

17:30

Close

19:30

Reception