Wednesday 9 July

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11:00

Registration and coffee

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11:30

Official Opening

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Bob Boucher, Vice-Chancellor, University of Sheffield

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11:45

Oral Communications

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Chairs: Tim Chambers (London, UK)/Greg Mundy (San Antonio TX, USA)

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11:45

OC1 LIMITIN, A TYPE-I INTERFERON-LIKE CYTOKINE, INHIBITS OSTEOCLASTOGENESIS WITHOUT AFFECTING MACROPHAGE PROLIFERATION AND FUNCTION

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T Sato, Y Hakeda. Department of Oral Anatomy, Meikai University, School of Dentistry, Saitama, Japan

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11:57

OC2 MATRIX METALLOPROTEINASE INHIBITION DOES NOT RECAPITULATE THE ACTION OF CHEMICALLY MODIFIED TETRACYCLINES ON OSTEOCLAST LINEAGE CELLS

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S G Holmes^[1], D J Buttle^[2], N J Bishop^[1], P S Grabowski^[1]. ^[1]Academic Unit of Child Health; ^[2]Division of Genomic Medicine, University of Sheffield, UK

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12:09

OC3 ZOLEDRONIC ACID INHIBITS ADHESION OF BREAST AND PROSTATE CANCER CELLS VIA INHIBITION OF PROTEIN PRENYLATION

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J P Coxon, L M Pickering, K W Colston. Department of Cellular & Molecular Medicine, St George's Hospital Medical School, London, UK

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12:21

OC4 VISUALISATION OF THE UPTAKE OF A NOVEL FLUORESECENT BISPHOSPHONATE INTO INTRACELLULAR VESICLES IN RESORBING OSTEOCLASTS AND J774 CELLS

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F P Coxon, J Langton, M J Rogers. Bone Research Group, University of Aberdeen, UK

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12:33

OC5 DISTINCT REGULATION OF BONE AND MUSCLE MAINTENANCE DURING HINDLIMB SUSPENSION BY A CONCENTRIC RESISTANCE EXERCISE REGIMEN

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D S Perrien^[1], N S Akel^[1], D C Montague^[1], M Knox^[2], J D Fluckey^[2], E E Dupont-Versteegden^[2], C A Peterson^[2], L Suva^[1], D Gaddy^[1]. ^[1]Physiology and Biophysics, and Center for Orthopaedic Research, Orthopaedic Surgery; ^[2]Geriatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

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12:45

Lunch

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13:45

Symposium: New thoughts about old hormones

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Chairs: Cyrus Cooper (Southampton, UK)/Gordon Strewler (Boston MA, USA)

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13:45

IS1 Vitamin D: Mike Holick (Boston MA, USA)

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14:15

IS2 Parathyroid hormone: Ed Nemeth (Toronto, Canada)

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14:45

Tea and Posters

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16:00

Symposium: Hearts and bones

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Chairs: Richard Eastell (Sheffield, UK)/Mike Rogers (Aberdeen, UK)

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16:00

IS3 Statins and bone: Greg Mundy (San Antonio TX, USA)

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16:30

IS4 Atherosclerosis: an inflammatory disease with calcification: David Crossman (Sheffield, UK)

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17:00

IS5 The Barker Hypothesis: Early life influences on bone and cardiovascular diseases: Cyrus Cooper (Southampton, UK)

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17:30

Close

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19:30

Reception

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