ANNUAL MEETING, 3-5 July 2007, Aberdeen UK

Company Profiles

Abbott
The Alliance for Better Bone Health (Procter & Gamble Pharmaceuticals and sanofi-aventis)
Eli Lilly
Immunodiagnostic Systems (IDS)
Novartis
Nycomed
Pfizer
ProStrakan
Qados
Roche/GSK
Scanco
Servier
Shire Pharmaceuticals
SkyScan
Technoclone

Abbott

Abbott is a global, broad-based health care company devoted to discovering new medicines, new technologies and new ways to manage health. Abbott scientists are applying innovative monoclonal antibody technology to discover and develop novel therapies to treat diseases of the immune system including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and Crohn’s disease.

The Alliance for Better Bone Health (Procter & Gamble Pharmaceuticals and sanofi-aventis)

Eli Lilly

Eli Lilly and Company is one of the world's largest research-based pharmaceutical companies, dedicated to creating and delivering innovative pharmaceutical healthcare solutions that enable people to live longer, healthier and more active lives. Our research and development efforts constantly strive to address urgent unmet medical needs.
Eli Lilly and Company was founded in 1876 in Indianapolis, USA, and has had a long history of producing endocrine products, dating all the way back to the collaboration with Banting and Best and the introduction of the world's first insulin product in 1922.
Another element of Lilly's endocrine portfolio is growth hormone replacement. Lilly manufactures recombinant human growth hormone (somatropin) at Speke near Liverpool, UK. A full range of products and services is provided for the healthcare professional to use with their patients on growth hormone replacement therapy for both adults and kids.
To assist in the therapeutic management of Osteoporosis, Lilly has two products each catering for different patient needs, namely Raloxifene and Teriparatide.
Finally Lilly continues to focus significant resources on research into the endocrine area. For additional information about any of our endocrine products or services please come and talk to us at the Lilly stand or log on to the company website - www.lilly.com.

Immunodiagnostic Systems (IDS) - www.idsltd.com

Immunodiagnostic Systems (IDS) offers a range of esoteric immunoassay kits for clinical and research use. The company focuses in Bone & Mineral Metabolism and Growth Factor research, and engages in collaborative projects with researchers worldwide.

IDS is a leader in the field of Vitamin D analysis, offering both manual and automated 25(OH) Vitamin D methods, an award-winning 1,25-Dihydroxy Vitamin D RIA system, and now announces OCTEIA 1,25(OH)2 Vitamin D, an EIA employing the proven immunocapsule sample preparation.

IDS offers a full range of Bone & Skeletal products, including BoneTRAP® (Tartrate-Resistant Acid Phosphatase 5b), MouseTRAP™, RatTRAP™, Bone-Specific Alkaline Phosphatase (Ostase® BAP), Intact PTH, urinary DPD, RANKL & OPG for both clinical and research (animal) use.

IDS are also pleased to announce a NEW, UNIQUE Rat/Mouse PINP ELISA to quantify type I collagen formation in rat or mouse samples.

IDS OsteoSite™ antibodies include multiple forms of PTHrp, Cathepsin K, Osteoarthritis Matrix Antigen (a Collagen VI epitope) and a specific Osteoclast Antigen; the GroPep range has multi-species Growth Factor and GF-Binding Protein antibodies; and the Eurodiagnostica range has antibodies to many matrix antigens, neuropeptides and associated reagents.

Dentine discs are available for osteoclast activity studies in vitro, suitable for use in microtitre wells.

Novartis

Novartis is a company committed to the discovery and development of medicines in areas of unmet clinical need. The therapeutic areas that Novartis works in include cardiovascular and metabolism, neuroscience, respiratory, arthritis, bone, infectious diseases, transplantation and immunology and oncology. Our product pipeline is one of the strongest in the pharmaceutical industry and in the UK alone we spend around £1million per week on research and development

Nycomed

Nycomed is a Danish pharmaceutical company dedicated to meeting healthcare needs in Europe. The company provides specialist hospital products throughout the region and general practitioner and pharmacy medicines in some markets.
New products are sourced through licensing agreements and partnerships with research companies. Here Nycomed provides late-stage clinical development, registration and marketing. Nycomed employs about 3,500 people throughout Europe and Russia-CIS.
Nycomed has a strong heritage in osteoporosis with Calcichew and Calcichew D3 and now with Preotact and osteoporosis remains one of its key therapeutic areas for future development.

Pfizer

Pfizer Inc, the world’s largest research-based pharmaceutical company, discovers, develops, manufactures and markets prescription medicines in 11 therapeutic areas. Pfizer is also the world’s largest animal health company.
Pfizer Inc employs approximately 105,000 colleagues worldwide, all of whom are devoted to working for a healthier world. Pfizer conducts more biomedical research than any other corporation, and has 14,000 professionals working in six major R&D sites worldwide, including Sandwich in Kent. Pfizer’s research investment in 2005 was more than $7.4 billion.
In the UK, Pfizer Ltd has its UK business headquarters in Surrey and is the major supplier of medicines to the NHS.

ProStrakan

ProStrakan Group plc is one of Europe's fastest growing speciality pharmaceutical companies. It is engaged in the development and commercialisation of prescription medicines for the treatment of unmet therapeutic needs in major markets. The company markets a range of products in major EU markets through its commercial operations based in the UK, Germany, France, Spain, Sweden and BeNeLux and has its headquarters and R&D activities in Galashiels, Scotland.

Qados

Qados are the distributors of the Faxitron X ray imaging cabinets in the UK. These cabinets are widely used for imaging bone both during research or during routine work in the Histopathology Departments. Digital imaging options are also available from Qados, for example the EZ240 X ray scanner from NTB.

Qados also represents Cisbio International in the UK, Cisbio produce Quadramet which is for bone pain palliation after breast, prostrate or bladder cancer treatment. If you would like to look at the complete qados portfolio please visit www.qados.co.uk

Roche/GSK

Roche in the UK
Roche aims to improve people's health and quality of life with innovative products and services for the early detection, prevention, diagnosis and treatment of disease. Part of one of the world’s leading healthcare groups, Roche in the UK employs nearly 2,000 people in pharmaceuticals and diagnostics. Globally Roche is the leader in diagnostics, the leading supplier of medicines for cancer and transplantation and a market leader in virology. Find out more at www.rocheuk.com

GSK
GSK, one of the world's leading research-based pharmaceutical and healthcare companies, is committed to improving the quality of human life by enabling people to do more, feel better and live longer. All trademarks used or mentioned in this release are legally protected.

Scanco

Scanco Medical (www.scanco.ch) in the leading manufacturer of state-of-the-art micro-CT scanners (research and clinical use). The scanners, together with built-in analysis and visualization software provide for a 3-dimensional, rapid, non-destructive and comprehensive quantitative measurements. Scanco Medical also offers contract based scanning services for academic and industrial groups at facilities in the USA or in Switzerland.

Servier

Servier Laboratories Limited is the British Subsidiary of the Servier Research Group, a leading French based organisation specialising in ethical pharmaceuticals. Servier is currently within the top 15 largest pharmaceutical companies in the UK.
Servier’s product portfolio in the UK focuses on the therapeutic areas of Cardiovascular disease, Diabetes, Osteoporosis and soon Depression. Servier's R&D pipeline is extremely healthy having the potential to submit one product for license every year for the next 8 to 10 years. Servier UK and the whole Servier Research Group is set for dramatic growth over this period.
www.servier.co.uk

Shire Pharmaceuticals

Shire Pharmaceuticals Group plc (Shire) is a global specialty pharmaceutical company with a strategic focus on meeting the needs of the specialist physician and currently focuses on developing projects and marketing products in the areas of central nervous system (CNS), gastrointestinal (GI), and renal diseases. Shire has operations in the world's key pharmaceutical markets (US, Canada, UK, France, Italy, Spain and Germany) as well as a specialist drug delivery unit in the US.
For further information on Shire, please visit the Company’s website: www.shire.com

SkyScan

SkyScan is a fast growing company and one of the world's leading producers of micro-CT systems for a wide range of applications. SkyScan aims to bring to customers the newest technology, the best instrument quality and the highest level of support.
SkyScan can genuinely claim to be at the fore-front of the development of high performance micro-CT technology. Our research and development of 3D x-ray microscopy started in the early 1980s. This led to the first micro-CT imaging results being obtained in 1983-1987 and published in scientific journals and international conferences proceedings. Building on this early work, SkyScan was founded in 1996, and within a year we were manufacturing a commercially available micro-CT scanner with spatial resolution in the micron range. In 2001 we produced the first high-resolution in vivo micro-CT scanner for small animal imaging. And in 2005 SkyScan became the world's only supplier of a laboratory nano-CT scanner with submicron spatial resolution. Responding to demand from the growing community of micro-CT users, we are continually active in research and development into new methods for non-destructive 3D microscopy.

Technoclone

Technoclone Ltd is a specialist in the field of bone, cartilage and mineral metabolism immunoassays and is the exclusive distributor in the UK and Ireland of both the Metra® range of Bone Marker assay kits from Quidel, the Bone and Cartilage assay kits from Nordic Bioscience Diagnostics and Cartilage assays kits from Ibex Diagnostics.
The Nordic Bioscience range includes clinical tests for serum and urine CTX-I (CrossLaps®),N-MID Osteocalcin and urine CTX-II (CartiLaps®), as well as the preclinical RatLaps and CrossLaps for Culture CTX-I kits, Rat-MID Osteocalcin and serum and urine pre-clinical CartiLaps® (CTX-II) kits. Nordic Bioscience also supply bovine bone slices available in a range of sizes for different assay plates.
The Metra® range of ELISA assays includes a highly specific Bone Alkaline Phosphatase (BAP) assay, serum Osteocalcin, Collagen Type -1 C-Terminal propeptide (CICP), DPD and Total DPD, PYD, alpha-1 Helical Peptide and YKL-40, as well as a chromogenic Creatinine assay and other research reagents.
Details of new kits from both Nordic Bioscience and Quidel will be available at the BRS meeting including

• Metra® TRAcP 5b ELISA
• Alpha CrossLaps (CTX-I) for bone metastases
• Preclinical Total Aggrecan
• Preclinical PIINP for cartilage formation
• Preclinical Synovial Fluid CTX-II assay
• Metra® Osteoprotegerin

Technoclone also markets an extensive range of autoimmune assays in multiplex and ELISA format, Complement assays and research reagents and multiplex human cytokine assays.

Updated: 26-jun-07

© 2005   The Bone and Tooth Society - Secretary: Dr Tim Arnett email: [email protected]